Dr. Tsumoto is a full Professor in the Bioengineering, School of Engineering and in the Medical Proteomics Laboratory, Institute of Medical Science at the University of Tokyo. He is a prolific researcher who has authored over 350 peer-reviewed publications. Dr. Tsumoto is also an inventor and has filed over 10 patents with multinational corporations such as Roche Diagnostics, Ajinomoto, and Horiba.
His research interest includes antibody engineering, biomaterials, modulation of protein interactions for therapy, molecular interactions in living organisms, and small molecule drug discovery screening based on biophysical approaches.
Some highlights of his research include the identification of the role of arginine in manipulating proteins for therapy, physicochemical dissection of pore-forming toxin function, dissection of protein interactions, e.g. antibodies and receptors using isothermal titration calorimetry (ITC) and surface plasmon resonance (SPR), and the separation of antibodies through carbohydrate structure using FcR immobilized column.
Dr. Tsumoto’s recent research is on exploring the dynamics of metals in the cellular system and he is the director of the “Bio-metal” research program that is funded by the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan.
His research has led to numerous awards including the prestigious Japan Society for the Promotion of Science (JSPS) Prize. He is currently the president of the Protein Science Society of Japan, a director at the Japanese Biochemical Society, a councillor of both the Protein Society in the US, the Japan Society of Drug Delivery System, and the Biophysical Society of Japan, as well as member of other academic societies.
He obtained both his BS and PhD in biological chemistry from the University of Tokyo.